根据名称进行药物检索

Gengraf Capsules与肝功能障碍

Gengraf Capsules与肝功能障碍安全配伍检测的结果。

检测结果:

Gengraf Capsules <> 肝功能障碍

现实性: 23.07.2019 评论家: 医学副博士Shkutko P.M., in

通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com，在进行所选药物与这种伴发疾病互相作用检测时，发现一些会产生负面影响或对身体危害的禁忌症及副作用。

用户:

孢菌素是广泛代谢通过CYP450 3A酶的肝(一些GI和肾的新陈代谢)，主要是消除在胆和粪便。環孢菌素可以诱导剂量有关的肾毒性和肝毒性。肝毒性，通常注意到的第一个月期间的治疗(高剂量)的特征是海拔的肝酶和胆红素。减少化学水平通常的结果，与剂量的减少。治疗药应给予谨慎和剂量的修改被认为患者或易患肝功能障碍。临床监测的肝功能，特别是在管理高剂量，建议。

来源

"Product Information. Sandimmune (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Tredger JM "Using cyclosporine neoral immediately after liver transplantation." Ther Drug Monit 17 (1995): 638-41
Sewing K-F, Christians U, Kohlhaw K, et al "Biologic activity of cyclosporine metabolites." Transplant Proc 22 (1990): 1129-34
de Groen PC, McCallum DK, Moyer TP, Wiesner RH "Pharmacokinetics of cyclosporine in patients with primary biliary cirrhosis." Transplant Proc 20 (1988): 509-11
Christians U, Kohlhaw K, Budniak J, et al "Ciclosporin metabolite pattern in blood and urine of liver graft recipients." Eur J Clin Pharmacol 41 (1991): 285-90
"Product Information. Neoral Oral Solution (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Kassianides C, Nussenblatt R, Palestine AG, et al "Liver injury from cyclosporine A." Dig Dis Sci 35 (1990): 693-7
Awni WM, Kasiske BL, Heim-Duthoy K, Rao KV "Long-term cyclosporine pharmacokinetic changes in renal transplant recipients: effects of binding and metabolism." Clin Pharmacol Ther 45 (1989): 41-8
Vernillet L, Moulin B, Dadoun C, et al "Pharmacokinetics of cyclosporine A in patients with nephrotic syndrome." Transplant Proc 20 (1988): 529-35
Takaya S, Zaghloul I, Iwatsuki S, et al "Effect of liver dysfunction on cyclosporine pharmacokinetics." Transplant Proc 19 (1987): 1246-7

Gengraf Capsules

非专利名称: cyclosporine

品牌: Gengraf, Neoral, Sandimmune, Sandimmune

同义词: Gengraf (Capsules, Modified), Gengraf

Gengraf Capsules是什么？