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Fentanyl transdermal skin patch与呼吸抑制

Fentanyl transdermal skin patch与呼吸抑制安全配伍检测的结果。

检测结果:

Fentanyl transdermal skin patch <> 呼吸抑制

现实性: 23.07.2019 评论家: 医学副博士Shkutko P.M., in

通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com，在进行所选药物与这种伴发疾病互相作用检测时，发现一些会产生负面影响或对身体危害的禁忌症及副作用。

用户:

鸦片制剂可能产生重大的中枢神经系统和呼吸抑制的时间长短不一，特别是当鉴于在高剂量和/或通过快速静脉用药。呼吸暂停可能会导致减少呼吸系统驱动器以及增加道阻力，并且刚性呼吸的肌肉期间可能发生的迅速的四管理或在这些试剂中使用的感应麻醉。在治疗镇痛剂量，呼吸系统效应通常不是临床上的重要除患者在预先存在的肺损伤。治疗阿片剂应避免或给予极为谨慎，并开始在减少剂量的患者带来严重的中枢神经抑制；睡眠呼吸暂停;缺氧，缺氧症,或高血二氧化碳；上气管阻塞；慢性肺功能不全；有限的通气储备；或其他呼吸道疾病。在存在过度的呼吸道分泌物，使用阿片剂也可能有问题的，因为他们减少睫的活动和减少咳嗽的反射。小心外，还建议在患者可能在危险增加呼吸抑郁症，例如昏迷患者或那些有头部受伤，颅内损伤，或颅内压。临床监测的肺功能是建议，并设备，用于复苏，应立即可用的，如果非肠道或阻滞路线的使用。纳洛酮给予可以扭转的临床明显的呼吸抑郁症，这可能会延长根据阿片剂，累积剂量，给药途径。

来源

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