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Clonidine与低血压

Clonidine与低血压安全配伍检测的结果。

检测结果:

Clonidine <> 低血压

现实性: 23.07.2019 评论家: 医学副博士Shkutko P.M., in

通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com，在进行所选药物与这种伴发疾病互相作用检测时，发现一些会产生负面影响或对身体危害的禁忌症及副作用。

用户:

中央α-2肾上腺素受体激动剂，降低交感神经流出从中枢神经系统，从而在降低心率，外围和肾血管性性，并血压力。治疗这些药剂应给予谨慎地在患有低血压或条件可能加剧了降低血压并灌注，诸如冠状动脉不足，周围的血管疾病(例如，雷诺氏综合症)、脑血管疾病，或最近的心肌梗塞。

来源

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Mosley C, O'Connor DT, Taylor A, et al "Comparative effects of antihypertensive therapy with guanabenz and propranolol on renal vascular resistance and left ventricular mass." J Cardiovasc Pharmacol 6 (1984): s757-61
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"Product Information. Catapres (clonidine)." Boehringer-Ingelheim, Ridgefield, CT.
Greene CS, Gretler DD, Cervenka K, et al "Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine." Am J Emerg Med 8 (1990): 293-6
Fruncillo RJ, Gibbons WJ, Vlasses PH, Ferguson RK "Severe hypotension associated with concurrent clonidine and antipsychotic medication." Am J Psychiatry 142 (1985): 274
Bauer JH "Effects of guanabenz therapy on renal function and body fluid composition." Arch Intern Med 143 (1983): 1163-7
"Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
van Zwieten PA, Thoolen MJ, Timmermans PB "The hypotensive activity and side effects of methyldopa, clonidine, and guanfacine." Hypertension 6 (1984): 28-33