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Acunivive 30 Injection System与胃肠道毒性
Acunivive 30 Injection System与胃肠道毒性安全配伍检测的结果。
检测结果:
Acunivive 30 Injection System <> 胃肠道毒性
现实性: 23.07.2019
评论家: 医学副博士Shkutko P.M., in
通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com,在进行所选药物与这种伴发疾病互相作用检测时,发现一些会产生负面影响或对身体危害的禁忌症及副作用。
用户:使用酮咯酸是禁忌的患者活动的胃溃疡,最近的消化道出血或穿孔,或一个历史的胃溃疡病或肠胃道出血。 酮咯酸是一种有效的非甾体抗炎药(非甾体). 非甾体抗炎药可能会导致胃肠粘膜的损坏风险的出现是相关的两个剂量和持续时间的治疗。 严重的GI的毒性,例如出血溃疡和穿孔可以发生在任何时间,有或没有的警示症状,在治疗的患者酮咯酸。 治疗与酮咯酸应该予以考虑,并给予谨慎的患者的历史GI炎症或酗酒,尤其是如果他们是老年人和/或衰弱,因为这样的病人可以更容易受到胃肠毒性的非甾体抗炎药和似乎容忍溃疡出血不太好,比其他个人。 密切监测用于毒性过程中,建议酮咯酸的治疗,其中应限于5天不管给药途径。
来源
- Estes LL, Fuhs DW, Heaton AH, Butwinick CS "Gastric ulcer perforation associated with the use of injectable ketorolac." Ann Pharmacother 27 (1993): 42-3
- Fuller DK, Kalekas PJ "Ketorolac and gastrointestinal ulceration." Ann Pharmacother 27 (1993): 978-9
- Litvak KM, McEvoy GK "Ketorolac, an injectable nonnarcotic analgesic." Clin Pharm 9 (1990): 921-35
- Wolfe PA, Polhamus CD, Kubik C, Robinson AB, Clement DJ "Giant duodenal ulcers associated with the postoperative use of ketorolac: report of three cases." Am J Gastroenterol 89 (1994): 1110-1
- Wiedrick JE, Friesen EG, Garton AM, Otten NH "Upper gastrointestinal bleeding associated with oral ketorolac therapy." Ann Pharmacother 28 (1994): 1109
- Maliekal J, Elboim CM "Gastrointestinal complications associated with intramuscular ketorolac tromethamine therapy in the elderly." Ann Pharmacother 29 (1995): 698-701
- Buckley MM, Brogden RN "Ketorolac. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential." Drugs 39 (1990): 86-109
- Strom BL, Berlin JA, Kinman JL "Parenteral ketorolac and risk of gastrointestinal and operative site bleeding: a postmarketing surveillance study." JAMA 275 (1996): 376-82
- Quigley EMM, Donovan JP, Livingston WC "Ketorolac-related giant gastric ulcers." Am J Gastroenterol 89 (1994): 631-2
- "Product Information. Toradol (ketorolac)." Roche Laboratories, Nutley, NJ.
- Sacanella E, Munoz F, Cardellach F, Estruch R, Miro O, Urbanomarquez A "Massive haemorrhage due to colitis secondary to nonsteroidal anti-inflammatory drugs." Postgrad Med J 72 (1996): 57-8
- Singh G, Ramey DR, Morfeld D, Fries JF "Comparative toxicity of non-steroidal anti-inflammatory agents." Pharmacol Ther 62 (1994): 175-91
- Buchman AL, Schwartz MR "Colonic ulceration associated with the systemic use of nonsteroidal antiinflammatory medication." J Clin Gastroenterol 22 (1996): 224-6
Acunivive 30 Injection System
非专利名称: ketorolac
品牌: Sprix, Toradol
同义词: Ketorolac (nasal), Ketorolac (Nasal)
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