根据名称进行药物检索

Promacot与血液学毒性

Promacot与血液学毒性安全配伍检测的结果。

检测结果:

Promacot <> 血液学毒性

现实性: 23.07.2019 评论家: 医学副博士Shkutko P.M., in

通过权威的信息来源 Drugs.com、Rxlist.com、Webmd.com、Medscape.com，在进行所选药物与这种伴发疾病互相作用检测时，发现一些会产生负面影响或对身体危害的禁忌症及副作用。

用户:

吩噻可能很少引起血液毒性，包括粒细胞缺乏症、血小板减少，嗜曙红细胞增多，再生障碍性贫血、紫癜，粒细胞，而溶血性贫血。温和的白细胞减少可能发生的经常与大剂量超过延长的时期，但一般可逆转的，尽管继续处理。治疗与吩噻应给予谨慎，如果有的话，在患有先前存在的血恶液质或骨髓抑制。全血球计数应得到定期的，患者应当指示立即报告任何迹象或症状暗示的血恶液质，如发烧，喉咙痛，本地感染、出血，脸色苍白，头晕，或黄疸。大多数情况下，粒细胞缺乏症发生之间的第四个和第十个星期的治疗。

来源

Yassa R "Agranulocytosis in the course of phenothiazine therapy." J Clin Psychiatry 46 (1985): 341-3
"Product Information. Compazine (prochlorperazine)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Phenergan (promethazine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Rosenthal DS, Stein GF, Santos JC "Thioridazine agranulocytosis." JAMA 200 (1967): 81-2
"Product Information. Tacaryl (methdilazine)." Westwood Squibb Pharmaceutical Corporation, Buffalo, NY.
"Product Information. Trilafon (perphenazine)" Schering Corporation, Kenilworth, NJ.
"Product Information. Serentil (mesoridazine)" Boehringer-Ingelheim, Ridgefield, CT.
"Product Information. Temaril (trimeprazine)" Allergan Inc, Irvine, CA.
"Product Information. Vesprin (triflupromazine)" Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Torecan (thiethylperazine)" Roxane Laboratories Inc, Columbus, OH.
"Product Information. Mellaril (thioridazine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Stein P, Inwood M "Hemolytic anemia associated with chlorpromazine therapy." Can J Psychiatry 25 (1980): 659-61
Young A, Kehoe R "Two cases of agranulocytosis on addition of a butyrophenone to a long-standing course of phenothiazine treatment." Br J Psychiatry 154 (1989): 710-12
Aram H "Henoch-Schonlein purpura induced by chlorpromazine." J Am Acad Dermatol 17 (1987): 139-40
Zengotita H, Holt R "Neuroleptic drug-induced coagulopathy: mechanism of reaction and duration of effect." J Clin Psychiatry 47 (1986): 35-7
Holt R "Neuroleptic drug-induced changes in platelet levels." J Clin Psychopharmacol 4 (1984): 130-2
"Product Information. Prolixin (fluphenazine)." Bristol-Myers Squibb, Princeton, NJ.
Ben-Yehuda A, Bloom A, Lijhovetzky G, et al "Chlorpromazine-induced liver and bone marrow granulomas associated with agranulocytosis." Isr J Med Sci 26 (1990): 449-51
Holt RJ "Fluphenazine decanoate-induced cholestatic jaundice and thrombocytopenia." Pharmacotherapy 4 (1984): 227-9
"Product Information. Stelazine (trifluoperazine)" SmithKline Beecham, Philadelphia, PA.
"Product Information. Thorazine (chlorpromazine)." SmithKline Beecham, Philadelphia, PA.